
Welcome. Are you prepared to conquer the Rift like never before? Patch 25.5 is here, bringing a surge of transformative builds that are altering the meta. Whether you’re a seasoned veteran or a rising star, these OP setups will give you the edge you need to climb the ranks and crush your opponents. From Vex Top Lane to Hail of Blades Viego, we’ve got the most broken builds and rune setups that are tearing up solo queue and pro play alike.
Get ready to unleash your full potential and leave your enemies in the dust. Let’s dive into the best LoL Boost Tier List 10 most OP builds of Patch 25.5!
1. Vex Top Lane: The Bruiser Counterpick
Vex Top Lane is making waves as a hard counter to mobile top laners like Riven and Irelia. This build transforms Vex from a squishy mid-lane mage into a tanky bruiser who can dominate the top lane.
Core Build:
- Liandry’s Anguish (First Item)
- Winter’s Approach (Second Item)
- Riftmaker (Third Item)
Rune Setup:
- Grasp of the Undying (for sustain and tankiness)
- Electrocute (for early game kill pressure)
Why It Works:
Vex’s fear mechanic punishes mobile champions, making her a challenge for top laners who depend on dashes. The bruiser build also enables her to endure longer in extended battles, highlighting her versatility in both solo queue and professional matches.
2. Trundle with Youmuu’s Ghostblade: The Split-Push King
Trundle makes a comeback with a lethal twist, turning him into a strong split-push contender. Thanks to the enhancement of Youmuu’s Ghostblade, this build has become a viable option for Trundle enthusiasts.
Core Build:
- Ravenous Hydra (First Item)
- Youmuu’s Ghostblade (Second Item)
- Infinity Edge (Third Item)
Rune Setup:
- Grasp of the Undying (for short trades)
- Lethal Tempo (for extended fights)
Why It Works:
This build emphasizes stacking AD and critical hit chance, enabling Trundle to eliminate fragile targets swiftly while sustaining his strength in split-pushing. The lethality provided by Youmuu’s enhances his mobility and damage, facilitating rapid game progression.
3. Udyr with Arcane Comet: The Unconventional Jungler
Udyr is breaking the mold with an unexpected rune setup that’s proving to be extremely effective. Arcane Comet combined with Axium Arc makes Udyr a skirmishing powerhouse.
Core Build:
- Liandry’s Anguish (First Item)
- Dead Man’s Plate (Second Item)
- Unending Despair (Third Item)
Rune Setup:
- Arcane Comet (Keystone)
- Axium Arc (for increased R damage)
- Waterwalking (for map control)
Why It Works:
Udyr’s R ability slows enemies, ensuring that Arcane Comet lands consistently. This setup amplifies his skirmish power, making him a threat in early and mid-game fights.
4. Hail of Blades Viego: The Burst Assassin
Viego returns with a revamped rune setup that transforms him into a burst assassin. Hail of Blades has received buffs, making it the rune with the highest win rate for him.
Core Build:
- Trinity Force (First Item)
- The Collector (Second Item)
- Immortal Shieldbow (Third Item)
Rune Setup:
- Hail of Blades (Keystone)
- Sudden Impact (for bonus lethality)
- Treasure Hunter (for snowballing)
Why It Works:
By utilizing Hail of Blades, Viego can quickly take out fragile targets. This setup enables him to function more as an assassin, establishing him as a formidable danger during the mid-game.
5. Electrocute Akshan: The Early Game Menace
Akshan is thriving with Electrocute after its recent buffs. This rune setup gives him insane early-game kill pressure, making him a nightmare for enemy mid-laners.
Core Build:
- Statikk Shiv (First Item)
- The Collector (Second Item)
- Infinity Edge (Third Item)
Rune Setup:
- Electrocute (Keystone)
- Sudden Impact (for bonus lethality)
- Treasure Hunter (for snowballing)
Why It Works:
Akshan’s kill potential in the early game is enhanced by Electrocute, enabling him to accelerate victories rapidly. This build emphasizes burst damage, positioning him as a powerful player in the mid-lane.
6. Manamune Cassiopeia: The Side Lane Dominator
Cassiopeia is seeing a new build that replaces Archangel’s Staff with Manamune. This setup gives her incredible tower-taking power and makes her a split-push threat.
Core Build:
- Rod of Ages (First Item)
- Malignance (Second Item)
- Manamune (Third Item)
Rune Setup:
- Arcane Comet (Keystone)
- Axium Arc (for increased R damage)
- Transcendence (for ability haste)
Why It Works:
Manamune provides Cassiopeia with AD, which synergizes well with her auto-attacks during split pushes. This build is situational but extremely strong in the right scenarios.

7. Immortal Shieldbow Nilah: The Survivor
Nilah is seeing a shift in her core build, with Immortal Shieldbow becoming a viable alternative to The Collector. This build gives her more survivability in burst-heavy matchups.
Core Build:
- Immortal Shieldbow (First Item)
- The Collector (Second Item)
- Infinity Edge (Third Item)
Rune Setup:
- Conqueror (Keystone)
- Triumph (for sustain)
- Alacrity (for attack speed)
Why It Works:
Immortal Shieldbow provides Nilah with a lifesaving shield, making her more durable in team fights. This build is ideal against burst-heavy bot lanes.
8. Youmuu’s Ashe: The Attack Speed Monster
Ashe is excelling with a new build that prioritizes Youmuu’s Ghostblade. This configuration provides her with extraordinary attack speed and kiting capabilities, transforming her into a late-game powerhouse.
Core Build:
- Youmuu’s Ghostblade (First Item)
- Phantom Dancer (Second Item)
- Infinity Edge (Third Item)
Rune Setup:
- Lethal Tempo (Keystone)
- Presence of Mind (for mana sustain)
- Alacrity (for attack speed)
Why It Works:
This build enhances Ashe’s kiting capability and increases her attack speed, enabling her to inflict permanent slows on opponents while delivering significant damage.
9. Electrocute Pantheon Support: The Early Game Killer
Pantheon Support is adopting a new rune configuration with Electrocute, significantly enhancing his early-game kill potential. This setup positions him as a formidable threat in the bot lane.
Core Build:
- Sundered Sky (First Item)
- Black Cleaver (Second Item)
- Bloodsong (Item Upgrade)
Rune Setup:
- Electrocute (Keystone)
- Sudden Impact (for bonus lethality)
- Relentless Hunter (for map mobility)
Why It Works:
Electrocute amplifies Pantheon’s burst damage, allowing him to delete squishy targets in the early game. This build makes him a dominant force in the bot lane.
10. Trailblazer Fiddlesticks Support: The Underrated Engager
Fiddlesticks Support is an underrated pick with a unique build that focuses on disruption and team utility. This setup makes him a strong engage support in solo queue.
Core Build:
- Trailblazer (First Item)
- Solstice Sleigh (Item Upgrade)
Rune Setup:
- Aftershock (Keystone)
- Axium Arc (for increased R damage)
Why It Works:
Fiddlesticks’ ultimate, combined with Aftershock, makes him a tanky disruptor in team fights. This build is ideal for players looking to support their team with strong engagement.
Final Thoughts On LoL Best Guide
Patch 25.5 has brought some incredible new builds that are reshaping the meta. Whether you’re looking to dominate the top lane with Vex, burst down enemies with Hail of Blades Viego, or support your team with Trailblazer Fiddlesticks, these LoL Boost Tier List builds will give you the edge you need to climb the ranks.